MONAI before 1.6.0 Remote Code Execution via algo_from_pickle

{
  "id": "4b579ffd41f8b7c518c948049956347fe8d22a038ce4be4a89ce4b72135683d6",
  "url": "https://osv.dev/vulnerability/CVE-2026-100843",
  "method": "structured",
  "payload": {
    "kind": "advisory",
    "title": "MONAI before 1.6.0 Remote Code Execution via algo_from_pickle",
    "summary": "MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.",
    "evidence": "osv:CVE-2026-100843",
    "products": [],
    "severity": "high",
    "structured": {
      "id": "CVE-2026-100843",
      "aliases": [
        "CVE-2026-100843",
        "GHSA-qxq5-qhx6-94qw",
        "PYSEC-2026-4018"
      ],
      "metrics": [
        {
          "type": "CVSS_V4",
          "score": "CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N"
        }
      ],
      "affected": [
        {
          "ranges": [
            {
              "repo": "https://github.com/project-monai/monai",
              "type": "GIT",
              "events": [
                {
                  "introduced": "0"
                },
                {
                  "fixed": "eccefc57550b111ed781d82249dfe77872a0e918"
                }
              ],
              "database_specific": {
                "extracted_events": [
                  {
                    "range": [
                      {
                        "introduced": "0"
                      },
                      {
                        "fixed": "1.6.0"
                      }
                    ],
                    "source": "AFFECTED_FIELD",
                    "strategy": "StandardRange"
                  },
                  {
                    "cpe": "cpe:2.3:a:project-monai:monai:*:*:*:*:*:*:*:*",
                    "range": [
                      {
                        "introduced": "0"
                      },
                      {
                        "fixed": "1.6.0"
                      }
                    ],
                    "source": "CPE_RANGE"
                  }
                ]
              }
            }
          ],
          "versions": [
            "1.5.1",
            "1.5.0",
            "1.5.0rc1",
            "1.4.1rc1",
            "1.4.0",
            "1.4.0rc12",
            "1.4.0rc11",
            "1.4.0rc10",
            "1.4.0rc9",
            "1.4.0rc8",
            "1.4.0rc7",
            "1.4.0rc6",
            "1.4.0rc5",
            "1.4.0rc4",
            "1.4.0rc3",
            "1.4.0rc2",
            "1.4.0rc1",
            "1.3.3rc1",
            "1.3.1",
            "1.3.1rc8",
            "1.3.1rc7",
            "1.3.1rc6",
            "1.3.1rc5",
            "1.3.1rc4",
            "1.3.1rc3",
            "1.3.1rc2",
            "1.3.1rc1",
            "1.3.0",
            "1.3.0rc5",
            "1.3.0rc4",
            "1.3.0rc3",
            "1.3.0rc2",
            "1.3.0rc1",
            "1.2.0",
            "1.2.0rc7",
            "1.2.0rc6",
            "1.2.0rc5",
            "1.2.0rc4",
            "1.2.0rc2",
            "1.2.0rc1",
            "1.1.0",
            "1.1.0rc2",
            "1.1.0rc1",
            "1.0.0rc3",
            "1.0.0rc2",
            "1.0.0rc1",
            "0.9.1",
            "0.9.1rc5",
            "0.9.1rc4",
            "0.9.1rc3",
            "0.9.1rc2",
            "0.9.1rc1",
            "0.9.0",
            "0.9.0rc3",
            "0.9.0rc2",
            "0.9.0rc1",
            "0.8.1",
            "0.8.1rc5",
            "0.8.1rc4",
            "0.8.1rc3",
            "0.8.1rc2",
            "0.8.1rc1",
            "0.8.0",
            "0.8.0rc3",
            "0.8.0rc2",
            "0.8.0rc1",
            "0.7.0",
            "0.7.0rc5",
            "0.7.0rc4",
            "0.7.0rc3",
            "0.7.0rc2",
            "0.7.0rc1",
            "0.6.0",
            "0.6.0rc2",
            "0.6.0rc1",
            "0.5.2",
            "0.5.1",
            "0.5.0",
            "0.5.0rc5",
            "0.5.0rc4",
            "0.5.0rc3",
            "0.5.0rc2",
            "0.5.0rc1",
            "0.4.0",
            "0.4.0rc2",
            "0.4.0rc1",
            "0.3.0",
            "0.3.0rc4",
            "0.3.0rc3",
            "0.3.0rc2",
            "0.3.0rc1",
            "0.2.0",
            "0.2.0rc3",
            "0.2.0rc2",
            "0.2.0rc1",
            "0.1.0",
            "0.1.0rc2",
            "0.1.0rc1",
            "0.1a1.dev9",
            "0.1a1.dev8",
            "0.1a1.dev7"
          ],
          "database_specific": {
            "source": "https://storage.googleapis.com/cve-osv-conversion/osv-output/CVE-2026-100843.json"
          }
        }
      ],
      "modified": "2026-10-28T02:30:37.650952998Z",
      "provider": "osv",
      "references": [
        "https://github.com/CVEProject/cvelistV5/tree/main/cves/2026/100xxx/CVE-2026-100843.json",
        "https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-qxq5-qhx6-94qw",
        "https://nvd.nist.gov/vuln/detail/CVE-2026-100843",
        "https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-algo-from-pickle"
      ],
      "provider_metadata": {
        "cwe_ids": [
          "CWE-502"
        ],
        "cna_assigner": "VulnCheck",
        "osv_generated_from": "https://github.com/CVEProject/cvelistV5/tree/main/cves/2026/100xxx/CVE-2026-100843.json"
      }
    },
    "related_cves": [
      {
        "value": "CVE-2026-100843",
        "evidence": "/id"
      }
    ],
    "security_relevant": true,
    "severity_evidence": "/severity/0/score"
  },
  "source_id": "core-osv",
  "document_id": 504743,
  "published_at": "2026-09-27T01:28:38.803+00:00"
}